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Cover picture: Average surface representations and three-dimensional (3D) variability maps for major sulci in both brain hemispheres. High-resolution maps of anatomical variability in three dimensions are shown in color (high variability: red colors; low: blue colors) on average representations of major deep sulci in Talairach stereotaxic space. 3D representations are shown for 10 average sulci from corresponding hemispheres of six cryosectioned human subjects. Context is provided by a transparent surface-rendered model of the external cerebral cortex and by a horizontal-slice image at the level of the eye orbits and anterior commissure. The color maps encode the root mean square magnitude of the displacement vectors required to map the surfaces from each of the six subjects onto the average according to strict parametric criteria. 3D modeling and surface reconstruction techniques allow visualization of sulcal topography and greatly enhance the ability to appreciate complex spatial relationships. For details, see the article by Thompson et al. in this issue (pp. 4261-4274).
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