About the Cover
Cover picture: Motor terminals on dually
innervated Drosophila larval longitudinal muscles
double-labeled with monoclonal antibody 22C10
(green) and anti-synaptotagmin
(red). Synaptic vesicles labeled by
anti-synaptotagmin are found within presynaptic varicosities in regions
that exclude the 22C10 antigen, probably a component of the axonal
cytoskeleton. The large size of these synaptic boutons allows
significant morphological detail to be discernable by optical
microscopic methods. Using a panel of compartment-specific markers, and
shibirets mutants to arrest an intermediate
stage in synaptic vesicle recycling, Estes et al. (pp. 5443-5456) have
studied the localization and redistribution of dynamin within
individual synaptic boutons.
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Copyright © 2003 by Society for Neuroscience.
