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Cover picture: Layout of functional domains in cat primary visual cortex determined with optical imaging. The dark and light regions correspond to ocular dominance columns of the contralateral and ipsilateral eye, respectively. The colored lines are iso-orientation lines that were derived from an orientation preference map from the same cortical region. All cortical points along a line of a given color respond best to the same orientation of a visual stimulus. It can be seen that the ocular dominance and orientation preference maps are geometrically related; many pinwheel centers (points at which lines of all colors converge) are centered on ocular dominance columns, and iso-orientation lines often cross the borders between adjacent ocular dominance columns at right angles. For details, see the article by Hübener et al., in this issue (pp. 9270-9284).
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