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Cover Figure


Cover picture: Taste bud from the nasoincisor duct of the rat's palate, showing an optical reconstruction (14 1-µm optical sections) of immunofluorescence labeling for alpha -gustducin in several taste cells (green) on a background of a single optical section through the center of the taste bud, depicting cell nuclei stained with propidium iodide (red). alpha -Gustducin is a taste-specific G-protein that has been implicated in the transduction of both sweet and bitter stimuli. It is expressed in significantly more cells in taste buds of the rat's posterior tongue and palate, areas that are very sensitive to bitter and sweet stimuli, respectively, than in fungiform taste buds on the rat's anterior tongue, which are relatively insensitive to both classes of stimuli. See the article in this issue by Boughter et al. (pp. 2852-2858).
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