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Cover picture: Photomontage of the left retina of a macaque monkey showing a fresh lesion made by applying 25 spots, each 500 µm in diameter, at an energy level of 220 mW for 200 msec with a blue-green argon laser. The lesion was located in the temporal retina, straddling the horizontal meridian, from 6 to 12°. The appearance of this lesion after healing, 14 weeks later, is shown in Figure 11A (page 5447). In striate cortex, it reduced cytochrome oxidase activity in a location corresponding exactly to the retinotopic map (see Figure 12A, page 5448). The reduction in metabolic activity persisted for months after the lesion was made, casting doubt on the notion that much "fill-in" of cortical scotomas occurs after focal retinal lesions, except for that attributable to retinal healing. For details, see the article by Horton and Hocking, in this issue (pages 5433-5455).