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Cover picture: Electrical activity in green fluorescent protein (GFP)-expressing gonadotropin-releasing hormone (GnRH) neurons in brain slices of transgenic mice. Top right, Glutamate-evoked current in a nucleated patch (top fluorescence) obtained from a fluorescent GnRH neuron in the diagonal band of Broca (middle fluorescence). Middle right, Spontaneous action potentials in a whole-cell recording of a fluorescent GnRH neuron in the diagonal band of Broca. GnRH neurons send their axons caudally to the median eminence (bottom fluorescence), from which GnRH critical for reproductive function is secreted in a pulsatile manner into the hypothalamo-hypophyseal circulation. For details, including scales of the fluorescence insets, see the article by Spergel et al., in this issue (pages 2037-2050). Design and layout by Dr. Rolf Sprengel.