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Cover picture: Rendering of a snake motor bouton from 31 serial electron microscopy sections reveals that endocytic sites are near active zones. The bouton was cooled to 7°C and briefly stimulated in the presence of the endocytic probe FM1-43. The probe was then photoconverted into an electron-dense marker. Endocytosed clathrin-coated vesicles (white) containing FM1-43 remained near their sites of internalization because of low temperature. These sites were near active zones (red) scattered within the presynaptic membrane (yellow). The postsynaptic folds of the innervated muscle fiber are shown blue. A Schwann cell that capped the bouton is pink, whereas endosomes within the bouton are gray. For details, see the article by Teng and Wilkinson in this issue (pages 7986-7993).
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