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Cover picture: Presynaptic (in red) and postsynaptic (in blue) cells and fibers in the cochlear nucleus of the chick, the site of giant end bulb synaptic terminals of auditory nerve fibers. These synapses are apparent surrounding each spherical cell body. The electrophysiological traces show orthodromic responses of a postsynaptic cell in both current- and voltage-clamp conditions, illustrating that synaptic depression does not completely eliminate functional transmission. An important factor in minimizing depression is the high efficiency of glutamate transporters, which act during the trains of stimuli to remove glutamate and prevent desensitization of receptors. The music underlying the image is from Schumann's "Traumerei (Reveries)." For details, see the article by Tureek and Trussell, in this issue (pages 2054-2063).