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Cover picture: Outgrowth of thalamocortical projections revealed with DiI tracing from the dorsal thalamus in a Snap25 knock-out (KO) brain at embryonic day 18.5. A coronal section was photographed with two different filters to reveal the DiI label (red) and bisbenzimide counterstain (blue). Thalamic axons traversed the primitive internal capsule as an organized array of fiber bundles, then defasciculated and turned dorsally to run through the intermediate zone and into the subplate below the cortex. Within a single litter, individuals showed slight variation in their maturity, but there was no consistent difference between wild-type (WT), heterozygote (HT), and Snap25 KO brains in the state of advancement of the thalamocortical fibers. For details, see the article by Molnár et al. in this issue (pages 10313-10323).
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