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Cover picture: Distribution of cone transducin in the zebrafish retina (top) and eye movements used to identify zebrafish with mutations that affect retinal function (bottom). Brockerhoff et al. have identified a mutant zebrafish that does not express the  subunit of cone transducin. Cone photoreceptors in the mutant fail to respond to moderate intensity illumination as expected. However, they do respond to intense illumination via a novel phototransduction mechanism that is mediated by light-stimulated release of Ca²⁺ into the cone cytoplasm. For details, see the article by Brockerhoff et al. in this issue (pages 470-480).