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Cover picture: Snapshots of the distribution of
membrane potential in a cat cortical (layer VI) pyramidal neuron during
simulated in vivo activity. The colors indicate
the membrane potential (from violet,
80 mV, to
yellow,
25 mV; see scale). Time runs from left
to right, then top to bottom (steps of
0.5 msec, except for the first frame, which was taken 4 msec earlier).
The simulation shows a dendritic action potential that propagates
forward to the soma and evokes a backpropagating action potential in
all other dendrites. These forward-propagating action potentials may play an important role in the integrative properties of pyramidal neurons during in vivo-like states. For details, see the
article by Rudolph and Destexhe in this issue (pages 2466-2476).
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