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Cover picture: A mouse sciatic nerve node of Ranvier
double immunolabeled for voltage-dependent Na+ channels (red) and Kv1.2 K+ channels (green). The
normal sturcture and molecular organization of nodes
and axons require the cytoskeletal scaffolding protein βIV spectrin, which is specifically localized and highly
enriched at these sites. For details, see the article by
Yang et al. in this issue (pages 7230-7240).
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