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Cover picture: Two isolated human nuclei from the
brain of a normal individual, each showing trisomic
aneuploidy for chromosome 21 (chr21). The three
chromosome copies are painted with wholechromosome
paint (green) specific for the whole q
arm of chr21 and a point probe (red) specific for
chr21q22.13-q22.2 using fluorescence in situ
hybridization. For details, see the article by Rehen et
al. in this issue (pages 2176-2180.
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