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Cover picture: Confocal optical section through a Frizzled6-/- mouse organ of Corti immunostained for Frizzled3. Inner hair cells are at the bottom of the image and outer hair cells are at the top. The cuboidal pillar cells can be seen sandwiched between the inner hair cells and the first row of outer hair cells. Frizzled3 is localized asymmetrically in a small zone of plasma membrane in both the hair cells and pillar cells. For details see the article by Wang et al. in this issue ( pages 2147-2156).

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