PT  - JOURNAL ARTICLE
AU  - Aya Ben-Yakov
AU  - Yadin Dudai
TI  - Constructing Realistic Engrams: Poststimulus Activity of Hippocampus and Dorsal Striatum Predicts Subsequent Episodic Memory
AID  - 10.1523/JNEUROSCI.0702-11.2011
DP  - 2011 Jun 15
TA  - The Journal of Neuroscience
PG  - 9032--9042
VI  - 31
IP  - 24
4099  - http://www.jneurosci.org/content/31/24/9032.short
4100  - http://www.jneurosci.org/content/31/24/9032.full
SO  - J. Neurosci.2011 Jun 15; 31
AB  - Encoding of real-life episodic memory commonly involves integration of information as the episode unfolds. Offline processing immediately following event offset is expected to play a role in encoding the episode into memory. In this study, we examined whether distinct human brain activity time-locked to the offset of short narrative audiovisual episodes could predict subsequent memory for the gist of the episodes. We found that a set of brain regions, most prominently the bilateral hippocampus and the bilateral caudate nucleus, exhibit memory-predictive activity time-locked to the stimulus offset. We propose that offline activity in these regions reflects registration to memory of integrated episodes.