RT Journal Article SR Electronic T1 Globus Pallidus Discharge Is Coincident with Striatal Activity during Global Slow Wave Activity in the Rat JF The Journal of Neuroscience JO J. Neurosci. FD Society for Neuroscience SP 10058 OP 10063 DO 10.1523/JNEUROSCI.23-31-10058.2003 VO 23 IS 31 A1 Joshua A. Goldberg A1 Svetlana S. Kats A1 Dieter Jaeger YR 2003 UL http://www.jneurosci.org/content/23/31/10058.abstract AB The emergence of bursting and oscillations in the basal ganglia under normal and pathological conditions has attracted considerable interest, but the neural substrate of these patterns is poorly understood. Here we use multisite recordings in anesthetized rats to examine the relationship of globus pallidus (GP) spiking and striatal activity in relation to cortical slow-wave activity. We found that GP neurons displayed increased spike rates or bursts coincident with cortical activation and striatal up states. Furthermore, the onset of GP bursts typically coincides with transitions to striatal up states that precede striatal spiking. These data indicate that GP activity is driven by excitatory corticosubthalamic input during periods of synchronized bursting activity.