RT Journal Article
SR Electronic
T1 Next-Generation Optical Technologies for Illuminating Genetically Targeted Brain Circuits
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 10380
OP 10386
DO 10.1523/JNEUROSCI.3863-06.2006
VO 26
IS 41
A1 Karl Deisseroth
A1 Guoping Feng
A1 Ania K. Majewska
A1 Gero Miesenböck
A1 Alice Ting
A1 Mark J. Schnitzer
YR 2006
UL http://www.jneurosci.org/content/26/41/10380.abstract
AB Emerging technologies from optics, genetics, and bioengineering are being combined for studies of intact neural circuits. The rapid progression of such interdisciplinary “optogenetic” approaches has expanded capabilities for optical imaging and genetic targeting of specific cell types. Here we explore key recent advances that unite optical and genetic approaches, focusing on promising techniques that either allow novel studies of neural dynamics and behavior or provide fresh perspectives on classic model systems.