TY - JOUR T1 - Lbx1 Acts as a Selector Gene in the Fate Determination of Somatosensory and Viscerosensory Relay Neurons in the Hindbrain JF - The Journal of Neuroscience JO - J. Neurosci. SP - 4902 LP - 4909 DO - 10.1523/JNEUROSCI.0717-07.2007 VL - 27 IS - 18 AU - Martin A. Sieber AU - Robert Storm AU - Margaret Martinez-de-la-Torre AU - Thomas Müller AU - Hagen Wende AU - Katja Reuter AU - Elena Vasyutina AU - Carmen Birchmeier Y1 - 2007/05/02 UR - http://www.jneurosci.org/content/27/18/4902.abstract N2 - Distinct types of relay neurons in the hindbrain process somatosensory or viscerosensory information. How neurons choose between these two fates is unclear. We show here that the homeobox gene Lbx1 is essential for imposing a somatosensory fate on relay neurons in the hindbrain. In Lbx1 mutant mice, viscerosensory relay neurons are specified at the expense of somatosensory relay neurons. Thus Lbx1 expression distinguishes between the somatosensory or viscerosensory fate of relay neurons. ER -