RT Journal Article
SR Electronic
T1 Preferential Reactivation of Motivationally Relevant Information in the Ventral Striatum
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 6372
OP 6382
DO 10.1523/JNEUROSCI.1054-08.2008
VO 28
IS 25
A1 Carien S. Lansink
A1 Pieter M. Goltstein
A1 Jan V. Lankelma
A1 Ruud N. J. M. A. Joosten
A1 Bruce L. McNaughton
A1 Cyriel M. A. Pennartz
YR 2008
UL http://www.jneurosci.org/content/28/25/6372.abstract
AB Spontaneous “off-line” reactivation of neuronal activity patterns may contribute to the consolidation of memory traces. The ventral striatum exhibits reactivation and has been implicated in the processing of motivational information. It is unknown, however, whether reactivating neuronal ensembles specifically recapitulate information relating to rewards that were encountered during wakefulness. We demonstrate a prolonged reactivation in rat ventral striatum during quiet wakefulness and slow-wave but not rapid eye movement sleep. Reactivation of reward-related information processed in this structure was particularly prominent, and this was primarily attributable to spike trains temporally linked to reward sites. It was accounted for by small, strongly correlated subgroups in recorded cell assemblies and can thus be characterized as a sparse phenomenon. Our results indicate that reactivated memory traces may not only comprise feature- and context-specific information but also contain a value component.