RT Journal Article
SR Electronic
T1 Changes in the dendritic geometry of mouse superior cervical ganglion cells following postganglionic axotomy
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 3703
OP 3711
DO 10.1523/JNEUROSCI.07-11-03703.1987
VO 7
IS 11
A1 H Yawo
YR 1987
UL http://www.jneurosci.org/content/7/11/3703.abstract
AB The dendritic geometry of mouse superior cervical ganglion cells was studied over periods of up to 3 months after postganglionic axotomy. Intracellular injection of HRP showed that total dendritic length and complexity were reduced by 60–70%, on average, among cells whose postganglionic axons had been crushed 2 weeks before. Both parameters gradually recovered in parallel with ganglion cell reinnervation of the periphery. These results indicate that neuronal interactions with peripheral targets influence the configuration of ganglion cell dendrites throughout life. The implications of this conclusion are discussed.