TY - JOUR T1 - Persistent Spiking Activity Underlies Working Memory JF - The Journal of Neuroscience JO - J. Neurosci. SP - 7020 LP - 7028 DO - 10.1523/JNEUROSCI.2486-17.2018 VL - 38 IS - 32 AU - Christos Constantinidis AU - Shintaro Funahashi AU - Daeyeol Lee AU - John D. Murray AU - Xue-Lian Qi AU - Min Wang AU - Amy F.T. Arnsten Y1 - 2018/08/08 UR - http://www.jneurosci.org/content/38/32/7020.abstract N2 - Persistent activity generated in the PFC during the delay period of working memory tasks represents information about stimuli held in memory and determines working memory performance. Alternative models of working memory, depending on the rhythmicity of discharges or exclusively on short-term synaptic plasticity, are inconsistent with the neurophysiological data.Dual Perspectives Companion Paper:Working Memory: Delay Activity, Yes! Persistent Activity? Maybe Not, by Mikael Lundqvist, Pawel Herman, and Earl K. Miller ER -