Table 1.

Raw counts of the number of c-Fos positive cells in response to water, NaCl and MSG stimulation in the nTS of WT and P2X-dblKO animals

WaterNaCl
WTP2X-dblKOWTP2X-dblKO
MedialMidLateralMedialMidLateralMedialMidLateralMedialMidLateral
r1 D0.1 ± 0.10.0 ± 0.00.1 ± 0.10.3 ± 0.30.0 ± 0.00.0 ± 0.00.5 ± 0.40.6 ± 0.50.9 ± 0.60.5 ± 0.51.7 ± 1.11.3 ± 0.8
    V0.0 ± 0.00.3 ± 0.01.1 ± 0.50.1 ± 0.10.4 ± 0.40.0 ± 0.00.1 ± 0.10.8 ± 0.51.1 ± 1.00.8 ± 0.51.8 ± 1.32.3 ± 1.7
r2 D0.4 ± 0.20.1 ± 0.10.6 ± 0.20.3 ± 0.23.3 ± 2.14.6 ± 2.20.9 ± 0.42.8 ± 1.72.5 ± 2.21.5 ± 1.02.8 ± 2.11.0 ± 0.8
    V0.1 ± 0.10.5 ± 0.50.8 ± 0.51.7 ± 1.04.9 ± 1.75.3 ± 2.10.5 ± 0.32.3 ± 1.23.0 ± 1.31.0 ± 0.82.7 ± 2.01.7 ± 1.0
r3 D1.8 ± 0.82.1 ± 0.63.3 ± 1.13.0 ± 1.37.1 ± 2.74.3 ± 2.15.4 ± 3.012.5 ± 5.47.9 ± 4.23.0 ± 1.19.3 ± 3.63.8 ± 1.2
    V2.1 ± 1.12.8 ± 1.32.4 ± 0.31.7 ± 0.86.1 ± 2.06.0 ± 1.75.3 ± 2.59.5 ± 3.55.8 ± 2.00.8 ± 0.34.7 ± 2.14.2 ± 1.7
r4 D1.5 ± 0.54.5 ± 1.24.4 ± 1.86.6 ± 3.114.5 ± 5.610.9 ± 3.15.5 ± 2.013.0 ± 3.811.5 ± 4.65.3 ± 2.014.7 ± 4.411.5 ± 4.3
    V1.3 ± 0.44.6 ± 1.04.8 ± 1.45.4 ± 3.116.1 ± 9.313.7 ± 4.83.3 ± 1.47.6 ± 2.18.9 ± 2.44.7 ± 2.99.7 ± 2.710.0 ± 2.2
i1 D3.6 ± 1.58.3 ± 1.87.1 ± 1.716.1 ± 3.925.0 ± 5.6§12.1 ± 4.48.3 ± 2.421.6 ± 7.49.5 ± 1.89.8 ± 2.920.0 ± 6.111.8 ± 3.7
    V0.8 ± 0.26.1 ± 2.04.9 ± 1.48.4 ± 2.721.0 ± 5.3§15.9 ± 6.96.0 ± 2.513.9 ± 6.111.0 ± 2.86.7 ± 2.415.3 ± 5.310.7 ± 3.8
i2 D13.3 ± 5.28.1 ± 2.06.0 ± 1.923.0 ± 6.3§25.9 ± 6.010.1 ± 2.824.9 ± 9.827.8 ± 7.7*15.3 ± 7.622.8 ± 9.521.5 ± 5.111.0 ± 4.6
    V5.4 ± 2.58.3 ± 2.35.9 ± 1.820.3 ± 6.8§24.0 ± 4.5§13.6 ± 3.417.0 ± 5.224.7 ± 7.313.8 ± 5.014.7 ± 4.629.0 ± 7.412.3 ± 2.4
i3 D11.6 ± 3.96.9 ± 1.46.3 ± 1.627.7 ± 7.6§32.1 ± 6.6§30.3 ± 6.5§32.5 ± 6.4*32.0 ± 9.0*8.8 ± 1.932.2 ± 7.931.3 ± 3.812.5 ± 2.5
    V11.1 ± 3.17.5 ± 2.05.9 ± 1.927.3 ± 6.7§27.4 ± 5.2§19.4 ± 4.4§34.1 ± 7.6*25.4 ± 4.7*12.1 ± 6.526.8 ± 6.023.0 ± 3.512.7 ± 3.1
i4 D7.6 ± 2.99.6 ± 3.05.3 ± 2.021.6 ± 4.0§24.9 ± 5.1§4.9 ± 2.028.0 ± 6.1*34.0 ± 9.0*8.3 ± 1.835.0 ± 10.2*33.0 ± 7.89.8 ± 3.7
    V7.6 ± 3.911.0 ± 3.35.5 ± 1.217.3 ± 3.825.6 ± 5.4§6.3 ± 1.827.3 ± 5.8*28.0 ± 6.112.5 ± 4.127.7 ± 7.2*27.5 ± 7.813.2 ± 3.4
i5 D6.3 ± 1.38.8 ± 2.83.0 ± 0.824.6 ± 3.2§22.4 ± 6.3§7.9 ± 2.934.2 ± 8.2*28.0 ± 8.3*7.0 ± 2.228.3 ± 7.932.0 ± 6.15.5 ± 1.3
    V5.5 ± 1.811.8 ± 3.43.1 ± 1.014.3 ± 3.126.3 ± 5.5§10.3 ± 2.917.8 ± 4.230.4 ± 9.9*7.9 ± 1.217.0 ± 5.529.8 ± 7.56.8 ± 1.9
MSG
WTP2X-dblKO
MedialMidLateralMedialMidLateral
r1 D2.7 ± 1.36.8 ± 3.26.5 ± 3.00.3 ± 0.31.0 ± 1.01.2 ± 1.0
    V2.5 ± 1.37.3 ± 3.45.0 ± 2.30.5 ± 0.52.3 ± 1.81.8 ± 1.8
r2 D2.7 ± 1.610.8 ± 4.510.5 ± 5.02.2 ± 1.63.8 ± 3.32.3 ± 1.7
    V2.7 ± 1.48.5 ± 3.310.2 ± 6.32.7 ± 2.15.0 ± 3.81.5 ± 1.1
r3 D9.5 ± 4.216.5 ± 9.49.7 ± 5.21.2 ± 0.48.2 ± 3.28.8 ± 3.5
    V7.3 ± 3.213.2 ± 6.110.7 ± 4.61.8 ± 0.67.5 ± 2.18.2 ± 2.5
r4 D13.2 ± 2.142.7 ± 10.7*20.7 ± 8.73.8 ± 0.813.5 ± 3.811.0 ± 3.0
    V9.2 ± 2.826.0 ± 7.4*20.0 ± 6.43.8 ± 1.714.8 ± 2.99.5 ± 2.7
i1 D17.7 ± 6.049.2 ± 12.0*27.5 ± 7.6*17.5 ± 9.117.7 ± 4.115.2 ± 5.9
    V6.3 ± 2.035.7 ± 11.2*26.5 ± 10.2*4.2 ± 1.930.5 ± 17.212.0 ± 3.1
i2 D36.2 ± 8.5*40.3 ± 13.1*30.2 ± 11.6*40.2 ± 8.324.8 ± 3.910.0 ± 2.6
    V10.0 ± 3.937.0 ± 16.5*19.5 ± 7.918.7 ± 7.326.8 ± 6.012.2 ± 2.9
i3 D52.0 ± 12.5*34.2 ± 12.1*20.3 ± 6.141.2 ± 11.221.5 ± 2.412.3 ± 4.4
    V34.0 ± 7.1*36.0 ± 12.4*25.5 ± 8.625.7 ± 4.423.5 ± 3.48.0 ± 3.1
i4 D45.0 ± 13.4*58.0 ± 15.4*25.3 ± 10.3*32.2 ± 10.248.3 ± 12.6*5.0 ± 2.3
    V29.3 ± 4.3*49.2 ± 10.2*32.7 ± 11.0*21.2 ± 3.232.0 ± 6.010.3 ± 3.9
i5 D32.3 ± 8.0*44.3 ± 9.7*16.2 ± 5.934.3 ± 6.846.8 ± 12.8*5.5 ± 1.6
    V23.5 ± 3.542.7 ± 6.8*22.3 ± 7.317.3 ± 2.938.0 ± 4.74.3 ± 1.5
  • D, Dorsal; V, ventral.

  • *, Significantly different from water-evoked Fos-LI within each genotype;

  • , MSG-evoked c-Fos expression significantly different from NaCl-evoked c-Fos expression;

  • §, WT significantly different from P2X-dblKO.