Table 2.

Effects of ascorbic acid and its analogs on GABAρ1 responses

Compound% Potentiationnτact (s)τdeact (s)n
Control (GABA 0.3 μm)624.8 ± 1.623.5 ± 3.86
3 mm Asc139.5 ± 87.5**722.6 ± 2.628.1 ± 3.36
3 mm D-isoAsc33.5 ± 12.5*428.5 ± 2.533.4 ± 1.96
3 mm DHA−1.6 ± 4.2326.1 ± 2.832.0 ± 2.86
1.5 mm Asc(Ca)27.4 ± 4.8622.5 ± 2.527.4 ± 4.34

  • Potentiation (%) produced by ascorbic acid and its different analogs on GABAρ1 responses and values obtained for kinetic parameters in the presence of the different compounds.

  • ↵*p < 0.04,

  • ↵**p < 0.01.