Summary of antibodies used in this study
| Protein | Antibody | Epitope | Host/application | Source |
|---|---|---|---|---|
| Aβ | 3D6 | aa 1–5 requiring free N terminus | Mouse/IHC, ELISA | Eli Lilly and Co. |
| m266 | aa 13–28 | Mouse/ELISA | Eli Lilly and Co. | |
| 2G3 | aa 35–40 | Mouse/ELISA | Eli Lilly and Co. | |
| 21F12 | aa 33–42 | Mouse/ELISA | Eli Lilly and Co. | |
| panAβ | aa 15–30 | Rabbit/IHC | Invitrogen | |
| Aβ40 | aa 34–40 | Rabbit/IHC | Invitrogen | |
| Aβ42 | aa 36–42 | Rabbit/IHC | Chemicon | |
| APP | APP | Full-length, C terminal | Rabbit/IHC, WB | Invitrogen |
| Tau | HT7 | panTau | Mouse/IHC | Pierce |
| pAb Tau | panTau | Sheep/IHC | Pierce | |
| Tau46 | panTau | Mouse/WB | Cell Signaling | |
| AT8 | pS199, pS202, pT205 | Mouse/WB | Pierce | |
| AT100 | pS212, pT214 | Mouse/WB | Pierce | |
| AT180 | pT231 | Mouse/WB | Autogen Bioclear | |
| S199 | pS199 | Rabbit/IHC | Invitrogen | |
| T205 | pT205 | Rabbit/IHC | Invitrogen | |
| T231 | pT231 | Rabbit/IHC | Invitrogen | |
| S396 | pS396 | Rabbit/IHC | Invitrogen | |
| S422 | pS422 | Rabbit/IHC | Invitrogen | |
| PHF1 | pS396/pS404 | Mouse/IHC | Dr. P. Davies | |
| Neurofilament | NF-L | NF-L 68kD | Mouse/IHC | Sigma |
| Tubulin | α-Tubulin | α-Tubulin/C terminal | Mouse/WB | Sigma |
aa, Amino acids; IHC, immunohistochemistry; WB, Western blot.