Response parameters of MC-responsive STN neurons
| Control (N = 46) | 6-OHDA (N = 44) | ||
|---|---|---|---|
| Average firing rate | 11.8 ± 9.1 | p < 0.0002 | 20.3 ± 9.3 |
| Burst index, % | 35.0 ± 16.7 | p < 0.0001 | 54.1 ± 15.6 |
| Early excitation, n/N (%) | 44/46 (95.7%) | 39/44 (88.6%) | |
| Latency (ms) | 5.5 ± 1.3 | ns | 5.9 ± 1.6 |
| Duration (ms) | 6.5 ± 2.2 | p < 0.001 | 5.0 ± 1.8 |
| Strength (spikes) | 51.3 ± 32.3 | p < 0.02 | 36.7 ± 25.6 |
| Short inhibition | 10/46 (21.7%) | 5/44 (11.4%) | |
| Latency | 10.4 ± 2.3 | ns | 11.2 ± 1.3 |
| Duration | 9.6 ± 4.1 | ns | 8.4 ± 3.6 |
| Strength | 14.6 ± 9.8 | ns | 8.5 ± 4.8 |
| Late excitation | 35/46 (76.1%) | 31/44 (70.5%) | |
| Latency | 19.1 ± 3.8 | p < 0.05 | 16.7 ± 3.2 |
| Duration | 14.5 ± 6.8 | ns | 11.5 ± 5.1 |
| Strength | 124.5 ± 98.9 | p < 0.05 | 84.4 ± 74.3 |
| Long inhibition | 35/46 (76.1%) | 43/44 (97.7%) | |
| Latency | 40.1 ± 11.9 | p < 0.001 | 31.5 ± 7.3 |
| Duration | 134.9 ± 57.2 | p < 0.02 | 174.2 ± 67.6 |
| Strength | 104.1 ± 57.6 | p < 0.0001 | 298.7 ± 168.5 |
Statistics: Mann–Whitney U test. N, Number of neurons; ns, not significant.