Optic nerve of control and anti-NT-3-treated embryos
| Age | Optic nerve mean area (μm2) | Axonal density (n/1000 μm2) | Total number of axons | |||
|---|---|---|---|---|---|---|
| Control (n = 3) | Anti-NT-3 (n = 5) | Control (n =3) | Anti-NT-3 (n = 4) | Control (n = 2) | Anti-NT-3 (n = 5) | |
| E6 | 34,150 ± 2741 | 20,075* ± 5240 | 9867 ± 141 | 8611** ± 270 | 336,761 ± 23,806 | 176,912* ± 50,112 |
| E9 | 141,6671_a ± 3786 | 103,250** ± 10,340 | 20,240 ± 4108 | 11,014* ± 741 | 2,840,556 ± 553,058 | 1,138,174** ± 143,420 |
| E14 | 354,330 ± 51,228 | 161,800* ± 51,285 | 7334 ± 832 | 5360 ± 1435 | 2,573,033 ± 124,727 | 910,310** ± 446,000 |
↵F1_a In three embryos treated with anti-NGF-secreting hybridoma cells, the mean optic nerve area was 142,665 ± 6509 μm2.
*p < 0.005; **p < 0.001.