Proliferation and pyknosis in the trigeminal ganglion of wild-type and NT-3 deficient mice
| E11.5 | E13.5 | |||
|---|---|---|---|---|
| Wild type | Mutant | Wild type | Mutant | |
| BrdU+ | 10878 ± 2548 | 9047 ± 368 | 4528 ± 381 | 1820 ± 281† |
| % BrdU+ | 30.4 ± 0.7 | 28.7 ± 1.1 | 13.6 ± 1.1 | 7.6 ± 1.1† |
| % Pyknotic | 3.2 ± 1.5 | 6.1 ± 2.5* | 3.0 ± 0.5 | 8.2 ± 2.5† |
BrdU+ is reported as the mean ± SD of counts of cells immunopositive for BrdU incorporation in three animals in each group. % BrdU+ is calculated as the mean percentage ± SD of BrdU-positive cells relative to numbers of precursors. % Pyknotic is reported as the mean ± SD of the percentage of pyknotic profiles relative to total cells for five animals in each group.
↵* p < 0.05, one-tailed Student’s t test;
↵† p < 0.01.