Simulated and experimental AMPA receptor kinetic parameters
| Parameter | Data | Stimulation | Data source |
|---|---|---|---|
| MaxPo | 0.57 ± 0.01 | 0.58 | see Results |
| 20–80% rise time (10 mm glu) | 129 ± 22 μsec | 145 μsec | Fig.8 |
| τdeact | 2.0 ± 0.6 msec | 1.94 msec | Fig.8 |
| τdes | 10.3 ± 4.1 msec | 10.1 msec | Fig.8 |
| τrec | 60.6 ± 12.8 msec | 60.1 msec | Fig.8 |
| Steady-state/peak | 0.19 ± 0.08 | 0.19 | Fig.8 |
| EC50 for l-glu | 482 ± 196 μm | 462 μm | Patneau and Mayer (1990) |
| Cooperativity (n) of glu binding | 1.1 | 1.2 | Patneau and Mayer (1990) |
| τreplace (glu vs KYN) | 389 ± 97 μsec | 416 μsec | Fig. 10 |
| Race (glu vs glu/KYN | 8.1 ± 1.9% | 9.0% | Fig. 9 |