Psychostimulant-induced rGβ1 mRNA changes in different brain regions
| Drugs | Striatum + accumbens | Prefrontal cortex | Thalamus + hypothalamus | Hippocampus |
|---|---|---|---|---|
| Cocaine (50 mg/kg, i.p.) | 246 ± 48 (n = 9) | 145 ± 45 (n = 6) | 96 ± 30 (n = 6) | 108 ± 47 (n = 6) |
| d-Amphetamine (7.5 mg/kg, i.p.) | 218 ± 63 (n = 9) | 72 ± 31 (n = 6) | 81 ± 26 (n = 6) | 337 ± 79 (n = 5) |
Values represent mean percentage of control ± SEM; rGβ1 mRNA levels were normalized to levels of expression of β-actin.