Table 1.

Expression highlights for RGS subtype mRNAs

RGS subtypeRegions and cell types where most enriched
RGS3Principal thalamic relay nuclei and white matter
RGS4Cortex, thalamus, and striatum, but noticeably low in hippocampus
RGS5Paraventricular and supraoptic nuclei of hypothalamus, basomedial amygdala, and glia
RGS6Olfactory bulb, scattered striatal cells, medial habenula, reticular thalamic, subthalamic, and pontine nuclei
RGS7Widespread, relatively high in cerebellar granule cells
RGS8Widespread, extremely dense in cerebellar Purkinje cells; relatively dense in basal ganglia-related brainstem nuclei
RGS9Extremely dense in caudoputamen, nucleus accumbens, and olfactory tubercle; relatively dense in medial hypothalamus
RGS10Extremely dense in dentate gyrus granule cells; relatively dense in superficial layers of neocortex and dorsal raphe
RGS11Subfornical organ and locus coeruleus