Table 1.

Immunoreactivities of glutamate transporter subtypes in fetal and postnatal rat CNS

GLASTGLT-1EAAC1EAAT4
E15E18P1P10P24AdE15E18P1P10P24AdE15E18P1P10P24AdE15E18P1P10P24Ad
Neocortex
 Marginal zone±±±±++++
  Layer 1±±++±++++++++++++±±+±
 Cortical plate±++
  Layer II±±+++++++++++±±±±
  Layer III±±++++++++++++±±+±
  Layer IV±±+++++++++++±±±±
  Layer V±±++++++++++++±±+±
  Layer VI±±+++++++++++++±±±±
Intermediate zone±±±
 Cerebral white matter±±±+±±++±+±±
Ventricular and subventricular  zones±±+±±±±±
Hippocampus±±+±++
 Stratum moleculare-lacunosum±±+++++++++++++±+±
 Stratum radiatum±±++++++++++++±+±
 Stratum pyramidale±±±±+++++++±±±±
 Stratum oriens±±+++++++++++++±+±
 Granular layer±±±±+++++++±±±
Olfactory bulb±±±±++±±++++++/±++++±±±
Ganglionic eminence±±+±±±±
Striatum±±±±++±+++++±++++++++±+±
Globus pallidus±±±±+++±+++++±++++++±±
Septum±±±±++±±±+++++±++++++±
Amygdala±±±±+++±+++++±++++++±±
Thalamus±±±±±++++++±±++++±±±
Hypothalamus±±±±++±+++++++±±++++
Tectum±±±±±+±+±+++++++++++
Medulla oblongata±±±±±±±++++++++++±±
Cerebellar primordium±±+
 Cerebellar cortex
  External granular layer
  Molecular layer+++++±++++++++++++
  Purkinje cell layer++++++++++++++++++++
  Internal granular layer±±±±±+++++
 Deep cerebellar nucleus±±±+++++++++±±
Spinal cord
 Posterior horn±±++++±++++++++++++++++++±±
 Ventral horn±±++±±±++++++++++++++++±
 White matter±±±±++++++++±±+++
  • Ad, Adult. Symbols designate no detectable (−), faint (±), moderate (+), and high (++) levels of immunoreactivity and not examined (/).