Agonist type | μ (DAMGO) | κ (U69593) | δ (DPDPE) | |||
---|---|---|---|---|---|---|
Number of cells inhibited | % inhibition | Number of cells inhibited | % inhibition | Number of cells inhibited | % inhibition | |
Cell group | ||||||
Control large cells | 2 /21 | 22.9 ± 3.6% | 1 /17 | 18.4% | 0/15 | 0 |
Axotomized large cells | 1 /18 (n.s.) | 20.6% (n.s.) | 2 /19 (n.s.) | 22.5 ± 2.1% (n.s.) | 0/12 (n.s.) | 0 |
Control medium cells | 14 /24 | 28.0 ± 1.9% | 9 /21 | 30.4 ± 2.0% | 0/20 | 0 |
Axotomized medium cells | 3 /21 | 18.5 ± 2.8% | 8 /18 (n.s.) | 29.9 ± 2.2% (n.s.) | 0/21 (n.s.) | 0 |
(p < 0.05) | (p < 0.02) | |||||
Control small cells | 15 /25 | 34.8 ± 2.3% | 14 /24 | 33.7 ± 2.1% | 0/21 | 0 |
Axotomized small cells | 5 /24 | 22.6 ± 2.3% | 12 /20 (n.s.) | 33.7 ± 2.0% (n.s.) | 0/18 (n.s.) | 0 |
(p < 0.01) | (p < 0.003) |
χ2 test was used for significance of difference between numbers of cells responding, and Student’s unpairedt test was used for significance of difference between percentage inhibition of IBa before and after axotomy. Percentage inhibition was calculated only from responding cells. n.s., Not significant.