Drug | Tail flick suppression | No tail flick suppression | p |
---|---|---|---|
Saline | 103 ± 8% | ||
Morphine (≤1 mg/kg) | 107 ± 4% | 114 ± 6% | n.s. |
Morphine (≥2 mg/kg) | 95 ± 11% | 190 ± 65% | n.s. |
The numbers are the mean ± SE of the serotonergic cell discharge, expressed as a percentage of baseline. p values are from unpaired t tests. A value of p < 0.05 is considered significant. Nonsignificant differences are marked n.s.