Rate constants for the kinetic scheme assumed for AMPA and NMDA receptors
| Forward rate constants | Backward rate constants | ||||
|---|---|---|---|---|---|
| AMPA | NMDA | AMPA | NMDA | ||
| kon(m−1sec−1) | 4.59 × 106 | 10 × 106 | koff1(sec−1) | 4.26 × 103 | 4.7 |
| kon2(m−1sec−1) | 28.4 × 106 | 5 × 106 | koff2(sec−1) | 3.26 × 103 | 9.4 |
| β (sec−1) | 4.24 × 103 | 46.5 | α (sec−1) | 900 | 91.6 |
| kd+1 (sec−1) | 2.89 × 103 | 0 | kd−1(sec−1) | 39.2 | 0 |
| kd+2 (sec−1) | 172 | 8.4 | kd−2(sec−1) | 0.727 | 1.8 |
| kd+3(sec−1) | 17.7 | 0 | kd−3(sec−1) | 4 | 0 |
| kd+4(m−1sec−1) | 1.27 × 106 | 0 | kd−4(sec−1) | 45.7 | 0 |
| kd+5(sec−1) | 16.8 | 0 | kd−5(sec−1) | 190.4 | 0 |
The values are taken from Jonas et al. (1993) and Lester and Jahr (1992), respectively.