FG-labeled profiles in control and arthritic rats
| L2 | L3 | L4 | L5 | |||||
|---|---|---|---|---|---|---|---|---|
| Saline | AIA | Saline | AIA | Saline | AIA | Saline | AIA | |
| Spinoreticular neurons | ||||||||
| FG | 19.3 ± 4.1 | 18.3 ± 3.9 | 18.0 ± 1.8 | 24.3 ± 4.3 | 12.5 ± 2.2 | 16.8 ± 5.3 | 9.75 ± 1.3 | 13.0 ± 4.24 |
| TrkA-IR | 6.7 ± 0.9 | 8.0 ± 2.4 | 2.5 ± 0.3 | 10.5 ± 3.0* | 1.8 ± 0.5 | 6.8 ± 0.8* | 0.8 ± 0.5 | 4.5 ± 1.7 |
| Double-labeled | 2.25 ± 0.85 | 5.25 ± 1.97 | 0.25 ± 0.25 | 6.50 ± 3.30* | 0.0 ± 0.0 | 3.25 ± 1.49* | 0.0 ± 0.0 | 1.25 ± 0.95 |
| Spinothalamic neurons | ||||||||
| FG | 10.8 ± 1.4 | 7.5 ± 0.4 | 20.0 ± 3.1 | 13.3 ± 2.3 | 19.8 ± 5.1 | 11.7 ± 1.8 | 11.8 ± 0.9 | 8.7 ± 3.0 |
| TrkA-IR | 3.3 ± 0.5 | 3.5 ± 0.4 | 2.8 ± 0.3 | 7.0 ± 3.0* | 2.5 ± 0.3 | 4.0 ± 0.0* | 0.75 ± 0.5 | 0.7 ± 0.7 |
| Double-labeled | 0.50 ± 0.29 | 0.5 ± 0.35 | 1.25 ± 0.63 | 1.33 ± 0.76 | 1.00 ± 0.40 | 0.33 ± 0.33 | 0.0 ± 0.0 | 0.33 ± 1.73 |
Mean number of FG-traced, TrkA-IR profiles, and double-labeled profiles in the spinal cord dorsal horn contralateral to the FG injection site. Results are given as mean number ± SEM in five coronal sections. Statistical analysis was performed using Mann–WhitneyU nonparametric test. *p < 0.05.