Table 1.

Parameter values for the unperturbed model

ParameterValues resulting in a free-running rhythm of 24.6 hrTransition from steady state to limit cycle at values
rM, mRNA production rate constant1.0 hr−10.27 hr−1
rP, protein production rate constant1.0 hr−10.02 hr−1
qM, mRNA degradation rate constant0.21 hr−10.08 hr−1
qP, protein degradation rate constant0.21 hr−10.08 hr−1
n, Hill coefficient2.01.27
m, nonlinearity in protein synthesis cascade3.01.81
τ, duration of protein synthesis cascade4.0 hr2.21 hr
k, scaling constant1