Reference values in wild-type and homozygous mutant mice
| Parameter | Wild-type mice | n | Homozygotes | n |
|---|---|---|---|---|
| Red blood cell (×104/mm3) | 953.3 ± 17.8 | 3 | 1056.3 ± 48.0 | 3 |
| White blood cell (×103/mm3) | 3.1 ± 0.9 | 3 | 2.8 ± 0.3 | 3 |
| Total protein (gm/dl) | 5.9 ± 0.4 | 3 | 5.7 ± 0.3 | 3 |
| Hematocrit (%) | 48.7 ± 0.7 | 3 | 50.7 ± 0.5 | 3 |
| Albumin (gm/dl) | 2.5 ± 0.1 | 3 | 2.7 ± 0.1 | 3 |
| Aspartate aminotransferase (U/I) | 240 ± 15.6 | 3 | 210 ± 10.6 | 3 |
| Blood urea nitrogen (mg/dl) | 33.8 ± 6.1 | 3 | 31.0 ± 2.1 | 3 |
| Creatinine (mg/dl) | 0.53 ± 0.15 | 3 | 0.47 ± 0.03 | 3 |
| Creatine phosphokinase (mg/dl) | 1365.3 ± 117.0 | 3 | 1180 ± 187.6 | 3 |
| Glucose (mg/dl) | 155.5 ± 14.1 | 6 | 151.3 ± 16.8 | 7 |
| Glutamic-oxaloacetic transaminase (U/I) | 84 ± 2.4 | 3 | 68 ± 5.1 | 3 |
| Glutamic-pyruvic transaminase (U/I) | 29 ± 5.7 | 3 | 23 ± 9.4 | 3 |
| NH3 (mg/dl) | 311 ± 72.1 | 6 | 348 ± 45.4 | 7 |
| Lactate dehydrogenase (U/I) | 526.3 ± 75.4 | 3 | 578.3 ± 77.0 | 3 |
| Triglycerides (mg/dl) | 179 ± 15.4 | 6 | 216.6 ± 26.3 | 7 |
| Total cholesterol (mg/dl) | 106.5 ± 5.1 | 6 | 107.3 ± 5.3 | 7 |
| Na+(mEq/l) | 139 ± 4.9 | 3 | 141.7 ± 1.2 | 3 |
| K+ (mEq/l) | 6.5 ± 0.4 | 3 | 7.8 ± 0.3 | 3 |
| Cl− (mEq/l) | 107.3 ± 4.3 | 3 | 105.5 ± 0.3 | 3 |
| Ca2+ (mEq/dl) | 5.37 ± 0.04 | 3 | 5.25 ± 0.06 | 3 |
| Total triiodothyronine (ng/ml) | 0.53 ± 0.04 | 6 | 0.61 ± 0.06 | 6 |
| Total thyroxine (ng/ml) | 41.25 ± 3.15 | 6 | 37 ± 1.43 | 6 |
| Growth factor (ng/ml) | 10.70 ± 2.95 | 4 | 9.90 ± 2.54 | 6 |
| Insulin-like growth factor I (ng/ml) | 475.75 ± 29.17 | 4 | 403.17 ± 33.40 | 6 |