High K+ affects growth cone morphology and actin organization
| Control1-a | K+ medium | |
|---|---|---|
| Filopodia length (μm) | 1.4 ± 0.4 (35) | 3.6 ± 1.2 (35)1-b |
| Actin rib length (μm) | 11.2 ± 2.1 (22) | 5.3 ± 2.5 (22)1-b |
| Lamellipodia width (μm) | 12.3 ± 1.3 (35) | 9.5 ± 1.6 (35)1-b |
↵F1-a From each growth cone (n= 5–7) analyzed, we measured the same filopodia, actin ribs, or lamellipodial regions just before treatment (Control) and 25 min after high K+ treatment (K+ medium). The values shown represent the mean ± SD, and the number of measurements are in parentheses.
↵F1-b Indicates significant difference from control data (paired t test; one-tailed; α = 0.01).