P2 receptor agonist and antagonist profiles and biophysical properties
| ATP (pA) | 2MeSATP (pA) | (n) | ATP (pA) | ATP ± PPADS (pA) | (n) | Length (μm) | Cm(pF) | Vz (mV) | (n) | |
|---|---|---|---|---|---|---|---|---|---|---|
| OHC | −1673 ± 275 | −1877 ± 315 | 16 | −1849 ± 565 | −602 ± 200 | 5 | 41.2–74.6 | 12.6–43.6 | −66.3 ± 1.4 | 17 |
| IHC | −809 ± 79 | −1092 ± 128 | 10 | −683 ± 98 | −231 ± 26 | 5 | 25.2–32.4 | 8.8–16.5 | −49.5 ± 1.8 | 10 |
Mean ± SEM; Cm, membrane capacitance; Vz, zero current potential. ATP, 2 MeSATP, PPADS, all 10 μm.