Degree of entorhinal axon choice for laminin
| Substrates compared | Category of axon choice | |||||
|---|---|---|---|---|---|---|
| Not classified | No preference | Slight preference | Clear preference | n | Significance | |
| Ephrin-A3 | 0 | 1 | 1 | 13 | 15 | p= 0.001 |
| Ephrin-A5 | 0 | 10 | 2 | 0 | 12 | NS |
| Mock | 1 | 9 | 0 | 0 | 10 | NS |
Entorhinal explants were grown on laminin-precoated carpets with single membranes stripes obtained from control (3T3), ephrin-A3, or ephrin-A5 cells. Under these conditions, entorhinal axons did not grow on ephrin-A3 membranes. Classification of choice preferences is described in Material and Methods. n, Number of explants; L, laminin; NS, not significant.