Number and perforation of synapses in CA1 and DG after cerebral ischemia
| Groups | Synapses/100 μm2 | Perforation (%) | ||
|---|---|---|---|---|
| CA1 | DG | CA1 | DG | |
| Sham | 35.51 ± 2.99 | 43.79 ± 12.83 | 4.35 ± 0.62 | 3.63 ± 0.97 |
| 4 hr | 32.943 ± 2.88 | 47.17 ± 6.58 | 5.82 ± 1.19 | 5.13 ± 1.27 |
| 24 hr | 39.00 ± 3.40 | 36.46 ± 2.32 | 6.63 ± 0.97* | 5.84 ± 2.08 |
| 7 d | 38.18 ± 2.12 | 5.44 ± 1.99 | ||
The samples are from sham-operated rats (sham) and rats subjected to 15 min of ischemia followed by 4 and 24 hr and 7 d of reperfusion. The number of synapses per 100 μm2 and the percent perforation are expressed as mean ± SD from three rats in each group.
*Significant difference (p < 0.05, Dunnett’s test) between sham-operated control and the postischemia groups.