Table 3.

Analysis of the frequency of GABAergic PSCs under different conditions

Experimental conditionNumber of PSCs per sec (mean ± SE)
Absence of TTX
 Control1.451  ± 0.263
 Choline (1 mm)2.524  ± 0.1523-a
 Control1.451  ± 0.263
 Choline (10 mm)2.636  ± 0.1653-a
 Control1.388  ± 0.393
 ACh (0.1 mm)2.152  ± 0.3603-a
 Control1.388  ± 0.393
 ACh (1 mm)3.138  ± 0.3423-a
Presence of TTX3-b
 Control1.331  ± 0.345
 Choline (10 mm)1.196  ± 0.409
 Control1.331  ± 0.345
 ACh (1 mm)1.432  ± 0.436

  • ↵F3-a p < 0.01, compared to respective control by paired t test; n = 5 in all groups.

  • ↵F3-b Slices were continuously perfused with TTX (0.5 μm)-containing ACSF.

  • Agonists were applied via the U-tube to the CA1 interneurons for 6–12 sec.