Table 1.

Expression of c-fos and zif 268mRNAs in the striatum, nucleus accumbens, and olfactory tubercle after apomorphine/SCH-23390 treatments (experiment 2)

	Infused side				Noninfused side
	S0 V	S0 A	S0.5 A	S10 A	S0 V	S0 A	S0.5 A	S10 A
c-fos expression
Middle striatum
Total area	2.5 ± 0.6	26.3 ± 2.7^1-167	12.6 ± 0.7**	1.8 ± 0.9**	2.5 ± 0.5	25.3 ± 3.5^1-167	17.8 ± 0.7*	2.3 ± 1.3**
Surrounding area	2.8 ± 0.5	25.5 ± 3.1^1-167	17.0 ± 0.7*	1.3 ± 0.9**	1.5 ± 0.5	24.5 ± 4.2^1-167	16.2 ± 0.6	1.8 ± 1.6**
Rostral striatum
Striatum	2.8 ± 0.8	20.0 ± 1.5^1-167	16.0 ± 1.1	2.0 ± 0.4**	2.8 ± 0.5	20.8 ± 1.0^1-167	17.4 ± 0.7*	2.8 ± 0.9**
Nucleus accumbens	4.8 ± 0.6	29.3 ± 4.2^1-167	17.0 ± 1.4**	4.3 ± 0.5**	5.0 ± 1.6	26.5 ± 4.3^1-167	18.8 ± 1.2	5.8 ± 0.9**
Olfactory tubercle	8.5 ± 2.1	35.3 ± 1.8^1-167	29.2 ± 3.3	8.5 ± 1.0**	7.5 ± 1.3	36.5 ± 4.5^1-167	31.6 ± 1.9	8.8 ± 1.6**
zif 268 expression
Middle striatum
Total area	24.8 ± 1.5	56.8 ± 2.5^1-167	36.2 ± 1.2**	24.5 ± 2.2**	28.8 ± 1.7	55.3 ± 3.3^1-167	44.6 ± 1.0**	28.3 ± 1.4**
Surrounding area	24.8 ± 1.3	56.0 ± 3.9^1-167	42.6 ± 1.8**	24.3 ± 2.1**	26.3 ± 1.9	55.0 ± 3.6^1-167	42.8 ± 1.0**	27.5 ± 1.7**
Rostral striatum
Striatum	30.5 ± 2.4	51.8 ± 3.7^1-167	39.8 ± 1.3**	29.0 ± 1.7**	35.5 ± 1.7	51.8 ± 3.1^1-167	41.4 ± 1.2*	30.0 ± 2.1**
Nucleus accumbens	36.0 ± 4.4	69.0 ± 4.3^1-167	52.2 ± 2.1**	31.5 ± 1.2**	39.0 ± 5.2	60.5 ± 6.6^1-167	52.6 ± 4.2	34.0 ± 2.9**
Olfactory tubercle	32.0 ± 3.8	52.3 ± 0.8^1-167	52.6 ± 3.2	29.3 ± 2.3**	33.0 ± 3.8	56.5 ± 4.1^1-167	55.2 ± 2.0	31.5 ± 2.1**

Mean density values (mean ± SEM) measured on the infused (left) and noninfused sides (right), at middle or rostral striatal levels, are given for animals that received an infusion of vehicle (S0), 0.5 μg (S0.5), or 10 μg (S10) of SCH-23390 into the right striatum before an injection of vehicle (V) or apomorphine (3 mg/kg, s.c.; A) (n = 4–5 each). For areas, see Figure 1.
↵F1-167 p < 0.01 versus S0 V; *p < 0.05, **p < 0.01 versus S0 A.