Group III mGluR agonists do not differentially affectd-[3H]aspartate uptake in mGluR4 knock-out (KO, −/−) and wild-type (+/+) mice cultures
| Treatment | Counts per minute/dish | |
|---|---|---|
| mGluR4 KO (−/−) | Wild-type (+/+) | |
| Basal | 26970 ± 436 | 28734 ± 537 |
| l-AP-4 (100 μm) | 27507 ± 294 | 27829 ± 542 |
| (R,S)-PPG (10 μm) | 26447 ± 665 | 27981 ± 875 |
| (R,S)-PPG (100 μm) | 27613 ± 604 | 27172 ± 465 |
Values are means ± SEM of four independent determinations.