Table 1.

Genes induced by NGF that are also responsive to either PDGFR/TrkA or PDGFR/p75

PDGFR/TrkA-stimulated gene expressionPDGFR/p75-stimulated gene expression
Encoded proteinFold inductionEncoded proteinFold induction
Bcl-x* 4.1Bcl-x* 4.5
GSTπ* 5.5GSTπ* 5
Clusterin5.9Clusterin3.2
Secretogranin3.3Secretogranin3.1
Neuron-specific enolase6.4Neuron-specific enolase5.1
NGF-inducible protein (VGF8A)45.7
Synapsin II* 3.1
UPAR23.8
Neuromodulin* 5.2
Acetylcholine receptor β-23.5
Cdk4(0.5)
  • * IκBα SS/AA decreases expression by >50%.