Table 1.

Genes induced by NGF that are also responsive to either PDGFR/TrkA or PDGFR/p75

PDGFR/TrkA-stimulated gene expressionPDGFR/p75-stimulated gene expression
Encoded proteinFold inductionEncoded proteinFold induction
Bcl-x*4.1Bcl-x*4.5
GSTπ*5.5GSTπ*5
Clusterin5.9Clusterin3.2
Secretogranin3.3Secretogranin3.1
Neuron-specific enolase6.4Neuron-specific enolase5.1
NGF-inducible protein (VGF8A)45.7
Synapsin II*3.1
UPAR23.8
Neuromodulin*5.2
Acetylcholine receptor β-23.5
Cdk4(0.5)
  • * IκBα SS/AA decreases expression by >50%.