Feeding and motor behavior after intra-accumbens treatments in food-deprived rats (15 min test)
| Behavioral indices | Treatment | |||
|---|---|---|---|---|
| Experiment 1 | Experiment 2 | |||
| VEH | AP-5/SCH | VEH | SCH | |
| Locomotion | 15 ± 2 | 15 ± 2 | 11 ± 2 | 4 ± 2* |
| Rears | 22 ± 2 | 30 ± 4 | 14 ± 3 | 8 ± 3 |
| Feeding duration (sec) | 530 ± 32 | 485 ± 26 | 618 ± 42 | 660 ± 39 |
| Average bout duration (sec) | 25 ± 2 | 28 ± 3 | 41 ± 5 | 89 ± 181-160 |
| Total intake (gm) | 3.6 ± 0.3 | 3.2 ± 0.2 | 4.3 ± 0.4 | 4.3 ± 0.3 |
Data represent means ± SEM. Locomotion is frequency of cage crossing. AP-5/SCH is the low-dose combination of the two drugs (AP-5, 0.5 nmol; SCH-23390, 0.3 nmol); SCH is the high dose of SCH-23390 (3 nmol). Average bout duration is the total duration per number of bouts.
↵* P < 0.004.
↵F1-160 P < 0.05.