Summary of spatiotemporal properties (no. waves/no. experiments/no. mice)
| Genotype | Age | Inter-event Interval (sec/wave) | Speed (μm/sec) | Initiation interval (sec/wave initiations per mm2) |
|---|---|---|---|---|
| +/+ | P2 | 120.8 ± 9.0 (114/9/4) | 165.6 ± 26.2 (20/4/4) | 25.2 ± 8.0 (58/3/3) |
| +/+ | E17 | 29.9 ± 10.0 (76/3/3) | 125.3 ± 3.5 (15/3/3) | Control: 3.4 ± 0.9 (139/3/3) |
| Curare: 7.5 ± 4.7 (94/3/3) | ||||
| α3−/− | P0–P3 | 53.1 ± 7.6 (57/6/4) | 143.2 ± 18.7 (15/3/3) | Control: 13.4 ± 3.3 (40/3/2) |
| Curare: 39.5 ± 9.7 (30/3/2) | ||||
| β2−/−β4−/− | P0 | 34.3 ± 7.9 (60/4/3) | 165.4 ± 12.1 (15/3/3) | 9.7 ± 2.8 (147/3/3) |
Inter-event interval is the period between consecutive correlated increases in [Ca2+]i in a small area (<200 μm2) of the retina. Wave speed was measured along a line perpendicular to the wave front (Feller et al., 1997). Initiation interval is the time between wave initiations within the entire imaged region (>1 mm2). For embryonic normal mice and α3−/− mice, the initiation intervals in the presence of curare are also listed.