Table 3.

Binding density of [¹²⁵I]RTI-55 (femtomoles per milligram of tissue) in rat Acb and dorsal STR 3 d after a 5 d treatment with cocaine and/or the selective κ-opioid receptor agonist U-69593

Treatment	Acb_shell	Acb_core	Dorsal STR	n
Vehicle + saline	18 ± 3	43 ± 7	70 ± 6	4
U-69593 + saline	13 ± 4^3-150	31 ± 7^3-150	52 ± 10^3-160	5
Vehicle + cocaine	23 ± 2	46 ± 1	66 ± 3	4
U-69593 + cocaine	14 ± 3^3-150	29 ± 6^3-150	49 ± 8^3-160	3

↵F3-150 p < 0.05 different from controls by two-way ANOVA (main effect of U-69593).
↵F3-160 p= 0.056 different from controls by two-way ANOVA (main effect of U-69593).