Region | Cerebral glucose use | ||
---|---|---|---|
Somatosensory pathways | COX-2 +/+ | COX-2 −/− | |
Trigeminal n. | L (Contralateral) | 129 ± 13 | 129 ± 10 |
R (Stimulated) | 199 ± 19* | 201 ± 15* | |
Ventrobasal thalamic n. | L | 206 ± 16* | 202 ± 8* |
R | 146 ± 11 | 142 ± 6 | |
Somatosensory cortex | L | 179 ± 7* | 172 ± 9* |
R | 129 ± 5 | 125 ± 8 | |
Forebrain | |||
Frontal cortex | L | 129 ± 8 | 129 ± 10 |
R | 130 ± 10 | 129 ± 12 | |
Auditory cortex | L | 152 ± 9 | 151 ± 6 |
R | 151 ± 9 | 152 ± 5 | |
Visual cortex | L | 126 ± 4 | 125 ± 5 |
R | 129 ± 4 | 124 ± 4 | |
Anterior thalamic n. | L | 151 ± 12 | 154 ± 10 |
R | 153 ± 10 | 156 ± 10 | |
Hypothalamus | L | 85 ± 11 | 90 ± 12 |
R | 89 ± 11 | 89 ± 11 | |
Hippocampus | L | 88 ± 9 | 82 ± 8 |
R | 89 ± 8 | 82 ± 9 | |
Caudate putamen | L | 160 ± 16 | 147 ± 12 |
R | 160 ± 14 | 146 ± 13 | |
Globus pallidus | L | 88 ± 10 | 88 ± 12 |
R | 88 ± 10 | 86 ± 12 | |
Corpus callosum | L | 64 ± 7 | 67 ± 5 |
R | 65 ± 6 | 66 ± 6 | |
Hindbrain | |||
Superior colliculus | L | 159 ± 13 | 154 ± 10 |
R | 160 ± 12 | 149 ± 11 | |
Inferior colliculus | L | 260 ± 38 | 256 ± 30 |
R | 258 ± 38 | 262 ± 30 | |
Pontine gray matter | L | 107 ± 9 | 109 ± 9 |
R | 109 ± 9 | 109 ± 8 | |
Medullary reticular formation | L | 116 ± 6 | 113 ± 11 |
R | 121 ± 7 | 117 ± 11 | |
Cerebellum | |||
Vermis | 121 ± 11 | 113 ± 8 | |
Cerebellar hemisphere | L | 91 ± 8 | 91 ± 11 |
R | 94 ± 9 | 92 ± 11 | |
Dentate n. | L | 178 ± 14 | 165 ± 10 |
R | 177 ± 13 | 168 ± 11 |
Mean ± SE; n = 6,*p < 0.01 from opposite side (paired t test). L, Left; R, right.