Table 1.

Levels of plasma steroids after ethanol administration

Steroid0 min20 min40 min80 min120 min150 min200 min
Allopregnanolone (ng/ml)0.068  ± 0.0161.35  ± 0.181.35  ± 0.0921.43  ± 0.0881.78  ± 0.540.74  ± 0.220.455  ± 0.18
Progesterone (ng/ml)2.02  ± 0.7893.3  ± 8.295.3  ± 6.0106  ± 3.767.2  ± 1644.2  ± 1115.2  ± 5.3
Corticosterone (ng/ml)54.3  ± 15386  ± 99517  ± 35597  ± 82481  ± 83391  ± 43174  ± 45
  • Ethanol was administered (2 gm/kg, i.p., 20% ethanol in saline w/v), and animals were euthanized 0, 20, 40, 80, 120, 150, or 200 min after injection. Animals euthanized at 0 min were killed immediately after injection. Each group represents a minimum of six animals, and all measurements were made from aliquots of the same plasma.